5 edition of Endothelial Modulation of Cardiac Function (Endothelial Cell Research) found in the catalog.
September 5, 1997
Written in English
|The Physical Object|
|Number of Pages||253|
The exposure of the endothelium to circulating proinflammatory mediators in infective or inflammatory states is associated with impaired endothelial function and inflammation has also been considered as a cardiovascular risk factor. 55,56 Elevated CRP levels were identified as a significant independent predictor of a blunted systemic. Abstract: The vascular endothelium is a monolayer of cells between the vessel lumen and the vascular smooth muscle cells. Nitric oxide (NO) is a soluble gas continuously synthesized from the amino acid L-arginine in endothelial cells by the constitutive calcium-calmodulin-dependent enzyme nitric oxide synthase (NOS).
Endothelium is the inner most cell layer of blood vessels. Endothelial cells make special barrier that separate blood from extravascular tissues. Intact endothelium regulates vascular tone and permeability and maintains non-inflammatory, anti-thrombotic surface. Through its ability to express pro-coagulants, anticoagulants, vasoconstrictors, vasodilators, cell adhesion molecules, and cytokines Author: Indranil Biswas, Gausal A. Khan. Endothelial dysfunction is characterized by nitric oxide dysregulation and an altered redox state. Oxidative stress and inflammatory markers prevail, thus promoting atherogenesis and hypertension, important risk factors for the development and progression of heart failure. There has been a reemerging interest in the role that endothelial dysfunction plays in the failing by: 1.
ENDOTHELIAL COLONY FORMING CELLS (ECFCS): IDENTIFICATION, SPECIFICATION AND MODULATION IN CARDIOVASCULAR DISEASES Lan Huang Submitted to the faculty of the University Graduate School in partial fulfillment of the requirements for the degree Doctor of Philosophy in the Department of Biochemistry and Molecular Biology, Indiana University. This study was investigated the role that endothelial function and systemic vascular resistance (SVR) play in determining cardiac function reserve during exercise by a new ambulatory radionuclide monitoring system (VEST) in patients with heart disease. The study population consisted of 32 patients. The patients had cardiopulmonary stress testing using the treadmill Ramp protocol and the by: 1.
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Paracrine and autocrine regulation of cardiac function by "endothelial" mediators is becoming important both physiologically and pathophysiologically. This volume brings the researcher completely up to date with all aspects of endothelial regulation and cardiac function. Endothelial Modulation of Cardiac Function.
Book January The goal of this book is to ensure that the new generation of research will profit from the wisdom of the past. The tools of. Endothelin and Cardiac Hypertrophy 6. Endothelium and Myocardial Growth and Fibrosis 7. Endothelial Regulation of Cardiac Myofilament Responsiveness to Calcium 8.
Natriuretic Peptides and Cardiac Function 9. Cardiac Inhibition of Angiotensin Converting Enzyme: Role of Kinins Nitric Oxide and Cardiac Contraction: Clinical Studies Book Description. Paracrine and autocrine regulation of cardiac function by "endothelial" mediators is becoming important both physiologically and pathophysiologically.
This volume brings the researcher completely up to date with all aspects of endothelial regulation and cardiac function. Endothelial function suffers prejudice proportional to total cholesterol, LDL-cholesterol, and HDL-cholesterol levels, hyperglycemia, physical inactivity, aging, blood pressure, and tobacco smoke exposition as Endothelial Modulation of Cardiac Function book been observed in several clinical studies.
It is also affected by family history for coronary disease and gender. Endothelial Modulation of Cardiac Function (Endothelial Cell Research) [Lewis, Malcolm J, Shah, Ajay M] on *FREE* shipping on qualifying offers. Endothelial Modulation of Cardiac Function (Endothelial Cell Research)Format: Hardcover.
The Endothelium: Modulator of Cardiovascular Function [Luscher, Thomas F., Vanhoutte, Paul M.] on *FREE* shipping on qualifying offers. The Endothelium: Modulator of Cited by: An accumulating body of experimental data supports the presence of a paracrine pathway for the modulation of myocardial function by cardiac endothelial cells.
Cardioactive substances released by endothelial cells include nitric oxide, endothelin-1, prostanoids, adenylpurines, natriuretic peptides, and other agents that have so far only been Cited by: Assessment of Endothelial Function.
Endothelial function may be tested by 2 main methods. The primary method provides more direct information on the functional capacity of the endothelium and involves evaluation of the endothelial cell response to direct stimulation of the endothelium and may be considered as endothelial stress tests.
Measuring Endothelial Function. Endothelial function is readily measured using both invasive and noninvasive modalities that have been subject of recent thorough reviews [8, 9].These methods are designed to assess vasodilation to pharmacologic stimuli (eg, acetylcholine or bradykinin), mechanical stimuli (shear), or by: REVIEW The endothelial cell in health and disease: its function, dysfunction, measurement and therapy BG Schwartz1, C Economides2, GS Mayeda2, S Burstein2 and RA Kloner1,3 1Heart Institute, Good Samaritan Hospital, Los Angeles, California, USA; 2Department of Cardiology, Good Samaritan Hospital, Los Angeles, California, USA and 3Department of Internal Medicine, Division of Cardiovascular.
63 Hambrecht R, Wolf A, Gielen S, Linke A, Hofer J, Erbs S, Schoene N, Schuler G. Effect of exercise on coronary endothelial function in patients with coronary artery disease. N Engl J Med. ; – Crossref Medline Google Scholar. 1. Circulation. Jan 25;(3) Endothelial function: cardiac events.
Lerman A(1), Zeiher AM. Author information: (1)Division of Cardiovascular Disease and Department of Internal Medicine, Mayo College of Medicine, First St SW, Rochester, MNUSA. @ PMID: Cited by: The postoperative endothelial function, measured with peripheral arterial tonometry as reactive hyperemia index (RHI) within 2 hours following surgery, will be compared in cardiac surgical patients randomized to receive human albumin or 6% HES solutions for intraoperative volume replacement.
The heart contains two types of endothelial cells; vascular and endocardial. Although similar, they show both anatomical and functional differences . The myocardium is richly vascularized, and it has been estimated that any cardiac myocyte is only a few microns away from a capillary vascular endothelial by: 1.
Cardiac Function. Cardiac and endothelial function were assessed using a pressure-volume conductance catheter system and isolated aortic rings respectively. Also, it is beyond the scope of this book to present a detailed consideration of the heart and cardiac physiology and function.
Summary. Recent studies in isolated cardiac preparations and the intact heart demonstrate that the endocardial and coronary vascular endothelium modulate myocardial contractile behaviour and cardiac pump function in a novel manner, mainly by influencing the duration of contraction and the onset of relaxation but without major effect on early systolic contractile by: 8.
Endothelium is a single layer of squamous endothelial cells that line the interior surface of blood vessels, and lymphatic vessels. The endothelium forms an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.
Endothelial cells form the barrier between vessels and tissue and control the flow of substances and fluid into and out of a on: Lining of the inner surface of blood.
DIETARY FACTORS THAT INFLUENCE ENDOTHELIAL FUNCTION. There has been growing interest in the role of nutritional factors in modulating endothelial function.
n−3 Fatty acids, antioxidant vitamins, folic acid, and l-arginine have been the primary focus of investigation. In this article, we summarize the epidemiologic and clinical trial data on Cited by: Moertl D, Hammer A, Steiner S, et al. Dose-dependent effects of omegapolyunsaturated fatty acids on systolic left ventricular function, endothelial function, and markers of inflammation in chronic heart failure of nonischemic origin: a double-blind, placebo-controlled, 3-arm study.
Am Heart J ; e1. Doxorubicin (Dox) is an effective anti-neoplasm drug, but its cardiac toxicity limits its clinical use.
Endothelial-to-mesenchymal transition (EndMT) has been found to be involved in the process of heart failure. It is unclear whether EndMT contributes to Dox-induced cardiomyopathy (DoIC). Calcitriol, an active form Vitamin D3, blocks the growth of cancer cells by inhibiting the Smad by: 1.The heart is composed of muscle cells (cardiomyocytes) that account for most of the heart mass and generate its pumping force.
Other cell types (fibroblasts, vascular endothelial cells, vascular smooth muscle cells) and the extracellular matrix also play key roles in cardiac function, both in health and in disease.
Excitation–contraction coupling links the electrical activation of Cited by: 3.Endothelial Albumin Transport In Vitro. Kinetics of Endothelial Ectonucleotidases. Adenosine Transport and Uptake by Cardiac and Pulmonary Endothelial Cells. Production of Tissue Factor.
Modulation of Endothelial Cell Proco-agulant and Fibrinolytic Activities by Inflammatory Mediators. Syn-thesis of von Willebrand Factor by Endothelial Cells.